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KMID : 1161520190230050335
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Animal Cells and Systems
2019 Volume.23 No. 5 p.335 ~ p.345
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Delay of cell growth and loss of stemness by inhibition of reverse transcription in human mesenchymal stem cells derived from dental tissue
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Lee Won-Cheol
Kim Dae-Young
Kim Mi-Jeong
Lee Hyeon-Jeong
Bharti Dinesh
Lee Sung-Ho
Kang Young-Hoon
Rho Gyu-Jin
Jeon Byeong-Gyun
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Abstract
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The present study investigated the cellular properties in the dental tissue-derived mesenchymal stem cells (DSCs) exposed to nevirapine (NVP), an inhibitor of reverse transcriptase (RTase). After a prolonged exposure of DSCs for 2 weeks, the population doubling time (PDT) was significantly (P?
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KEYWORD
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Human MSCs, reverse transcriptase, nevirapine, cell growth, differentiation
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